السبت 15 مايو 2021

Publications et Recherches du Dr Ahmed Chenna

Publications et Recherches du Dr Ahmed Chenna

Publications et Recherches du Dr Ahmed Chenna

Principal Scientist, Oncology Group, Monogram Biosciences Inc., LabCorp

Vous trouvez ci-dessous la liste des Publications et Recherches du Dr Ahmed Chenna :

Highly Sensitive Single Molecular Array Immunoassay Measurement of t-Tau, NF-L, GFAP, and UCH-L1 Biomarkers in Acute Concussion/Mild Traumatic Brain Injury (mTBI) Patient Serum …

A Chenna, C Petropoulos, J Winslow

Neurology 93 (14 Supplement 1), S19-S20

Molecular and Clinical Activity of CDX-3379, an Anti-ErbB3 Monoclonal Antibody, in Head and Neck Squamous Cell Carcinoma Patients.

U Duvvuri, J George, S Kim, D Alvarado, VM Neumeister, A Chenna, …

Clinical Cancer Research 25 (19), 5752-5758

Highly Sensitive Single Molecular Array Immunoassay Measurement of t-Tau, NF-L, GFAP, and UCH-L1 Biomarkers in Acute Concussion/Mild Traumatic Brain Injury (mTBI) Patient Serum …

A Chenna, C Petropoulos, J Winslow

Neurology 92 (15 Supplement), P2. 9-047

p95HER2–T cell bispecific antibody for breast cancer treatment.

IR Ruiz, R Vicario, B Morancho, CB Morales, EJ Arenas, S Herter, …

IR Ruiz, R Vicario, B Morancho, CB Morales, EJ Arenas, S Herter, …

Master key identification and feedback system.

GL Hagen, M Mueller, M Yeary, KC Booth

US Patent 10,010,949

Molecular and clinical activity of CDX-3379, an anti-ErbB3 monoclonal antibody, in head and neck squamous cell carcinoma: A preoperative” window of opportunity” study.

U Duvvuri, J George, S Kim, D Alvarado, V Neumeister, A Chenna, …

CANCER RESEARCH 78 (13)

Abstract CT058: Molecular and clinical activity of CDX-3379, an anti-ErbB3 monoclonal antibody, in head and neck squamous cell carcinoma: A preoperative” window of opportunity …

U Duvvuri, J George, S Kim, D Alvarado, V Neumeister, A Chenna, …

Cancer Research 78 (13 Supplement), CT058-CT058

Abstract LB-292: p95HER2-T cell bispecific antibody for breast cancer treatment.

R Vicario, IR Ruiz, B Morancho, CB Morales, S Herter, …

Cancer Research 78 (13 Supplement), LB-292-LB-292

p95HER2 methionine 611 carboxy-terminal fragment is predictive of trastuzumab adjuvant treatment benefit in the FinHer trial.

J Sperinde, W Huang, A Vehtari, A Chenna, PL Kellokumpu-Lehtinen, …

Clinical Cancer Research 24 (13), 3046-3052

Elevated TGFa levels in chronic mylogenous leukemia (CML) patient plasma measured by a highly sensitive single molecule array immunoassay.

CJPJWW Ahmed Chenna, Li Cai

Cancer Research 78(13 Supplement):3612-3612 78 (13), 3612-3612

High p95HER2/HER2 Ratio Associated With Poor Outcome in Trastuzumab-Treated HER2-Positive Metastatic Breast Cancer NCCTG N0337 and NCCTG 98-32-52 (Alliance).

ACDEAP Saranya Chumsri, Jeff Sperinde, Heshan Liu, Joseph Gligorov, Jean …

Clinical Cancer Research

Highly sensitive single molecular array immunoassay quantitation of neuronal proteins t-Tau, pTau231, Ab42, and Nf-L in CSF and Alzheimer’s disease plasma.

J Ahmed Chenna, Christos J Petropoulos

Society for Neuroscience 47th Annual Meeting

Adverse health effects of thirdhand smoke: from cell to animal models.

B Hang, P Wang, Y Zhao, A Sarker, A Chenna, Y Xia, AM Snijders, …

International journal of molecular sciences 18 (5), 932

Development of a proximity-based immunoassay to measure the PD1: PD-L1 complex in fixed samples.

G Wallweber, R Ravanera, A Chenna, D Stathas, W Huang, J Winslow, …

Cancer Research 76

Correlation of high p95HER2: HER2 ratio with poor outcome in two phase II clinical trials of trastuzumab-treated HER2-positive metastatic breast cancer.

S Chumsri, J Sperinde, H Liu, J Gligorov, JP Spano, A Moreno-Aspitia, …

Journal of Clinical Oncology 34 (15_suppl), 603-603

Abstract P3-07-09: Quantitative p95HER2 protein expression is predictive of trastuzumab response in HER2-positive metastatic breast cancer.

J Sperinde, B Bachmeier, JM Weidler, Y Lie, A Chenna, J Winslow, …

Cancer Research 76 (4 Supplement), P3-07-09-P3-07-09

Increased expression of HER2, HER3, and HER2: HER3 heterodimers in HPV-positive HNSCC using a novel proximity-based assay: implications for targeted therapies.

NI Pollock, L Wang, G Wallweber, WE Gooding, W Huang, A Chenna, …

Clinical Cancer Research 21 (20), 4597-4606

Prolonged response to trastuzumab in a patient with HER2-nonamplified breast cancer with elevated HER2 dimerization harboring an ERBB2 S310F mutation.

S Chumsri, J Weidler, S Ali, S Balasubramanian, G Wallweber, …

Journal of the National Comprehensive Cancer Network 13 (9), 1066-1070

Development of a sensitive and quantitative PD-L1 immunoassay superior to IHC with application in human FFPE tissue samples.

J Wallweber, A Chenna, R Ravanera, D Stathas, W Huang, C Petropoulos

Cancer Research 75

Association of ErbB/HER Biomarkers with antitumor activity of the anti-ErbB3/HER3 monoclonal antibody KTN3379 in SCCHN.

D Alvarado, J Wallweber, S Seibel, A Chenna, R Ravanera, W Huang, …

AACR Annual Meeting

Suite de la liste des Publications et Recherches du Dr Ahmed Chenna :

Correlation of trastuzumab treatment benefit with quantitative HER2 expression levels in HER2 positive metastatic breast cancer.

B Bachmeier, J Sperinde, JM Weidler, Y Lie, A Chenna, J Winslow, …

Journal of Clinical Oncology 33 (15_suppl), 593-593

Abstract P3-06-03: Quantitative p95HER2 and HER2 correlations with outcome in the FinHer trial.

J Sperinde, W Huang, A Vehtari, A Chenna, PL Kellokumpu-Lehtinen, …

J Sperinde, W Huang, A Vehtari, A Chenna, PL Kellokumpu-Lehtinen, …

HER2 over-expressing high grade endometrial cancer expresses high levels of p95HER2 variant.

WB Growdon, J Groeneweg, V Byron, C DiGloria, DR Borger, …

Gynecologic oncology 137 (1), 160-166

Quantitative HER2 and p95HER2 levels in primary breast cancers and matched brain metastases.

Neuro-Oncology

High HER2 expression correlates with response to the combination of lapatinib and trastuzumab.

M Scaltriti, P Nuciforo, I Bradbury, J Sperinde, D Agbor-Tarh, C Campbell, …

Clinical cancer research 21 (3), 569-576

Smoke: the hidden risks.

B Hang, A Chenna, L Gundel

CHEMISTRY & INDUSTRY 78 (10), 36-36

Quantitative measurements of tumoral p95HER2 protein expression in metastatic breast cancer patients treated with trastuzumab: independent validation of the p95HER2 clinical cutoff.

R Duchnowska, J Sperinde, A Chenna, M Haddad, A Paquet, Y Lie, …

Clinical Cancer Research 20 (10), 2805-2813

NNA, a thirdhand smoke constituent, induces DNA damage in vitro and in human cells.

B Hang, A Iavarone, C Havel, P Jacob III, P Villalta, B Matter, D Sharan, …

Abstracts of Papers of the American Chemical Society 247.

Abstract P6-11-07: Quantitative p95HER2 levels in primary breast cancers and in matched brain metastases.

R Duchnowska, J Sperinde, A Chenna, W Huang, J Weidler, J Winslow, …

Cancer Research 73 (24 Supplement), P6-11-07-P6-11-07

HER3, p95HER2, and HER2 protein expression levels define multiple subtypes of HER2-positive metastatic breast cancer.

A Lipton, L Goodman, K Leitzel, J Cook, J Sperinde, M Haddad, …

Breast cancer research and treatment 141 (1), 43-53

Quantitative measurements of p95HER2 (p95) protein expression in tumors from patients with metastatic breast cancer (MBC) treated with trastuzumab: Independent confirmation of …

R Duchnowska, J Sperinde, M Haddad, A Chenna, A Paquet, Y Lie, …

Journal of Clinical Oncology 31 (15_suppl), 604-604

Profiling HER3/ErbB3 activation in formalin-fixed, paraffin-embedded (FFPE) breast tumor samples that express high and low HER2/ErbB2 levels using proximity-based immunoassays.

J Wallweber, A Chenna, R Ravanera, W Huang, D Stathas, G Marshall, …

Cancer Research 73 (8 Supplement), 3029-3029

Thirdhand smoke causes DNA damage in human cells.

B Hang, AH Sarker, C Havel, S Saha, TK Hazra, S Schick, P Jacob III, …

Mutagenesis 28 (4), 381-391

Enhanced method for detecting and/or quantifying an analyte in a sample.

Y Badal, A Chenna, SH Tahir, Y Tan

US Patent 8,357,277

Correlation of quantitative p95HER2, HER2, and HER3 protein expression with pathologic complete response (pCR) in HER2-positive breast cancer patients (pts) treated with …

JC Villasboas, J Hurley, JM Weidler, A Paquet, CG Fernandez, …

Journal of Clinical Oncology 30 (27_suppl), 137-137

A comparative study of p95-HER2 carboxy terminal fragment (CTF) detected by immunohistochemistry and VeraTag assays in human breast tumors.

J Sperinde, A Chenna, J Zhang, V McWhorter, L Dierbeck, M Da Silva, …

Cancer Research 72 (8 Supplement), 687-687

A comparative study of p95-HER2 carboxy terminal fragment (CTF) detected by immunohistochemistry and VeraTag immunoassays in human breast tumors.

J Sperinde, A Chenna, J Zhang, V McWhorter, L Dierbeck, M Da Silva, …

American Association for Cancer Research (AACR) Annual Meeting, Mar

Profiling the HER3/PI3K pathway in breast tumors using proximity-directed assays identifies correlations between protein complexes and phosphoproteins.

A Mukherjee, Y Badal, XT Nguyen, J Miller, A Chenna, H Tahir, A Newton, …

PLoS One 6 (1), e16443

Benzene-derived N2-(4-hydroxyphenyl)-deoxyguanosine adduct: UvrABC incision and its conformation in DNA.

B Rodriguez, Y Yang, AB Guliaev, A Chenna, B Hang

Toxicology letters 193 (1), 26-32

A novel proximity assay for the detection of proteins and protein complexes: quantitation of HER1 and HER2 total protein expression and homodimerization in formalin-fixed …

Y Shi, W Huang, Y Tan, X Jin, R Dua, E Penuel, A Mukherjee, J Sperinde, …

Diagnostic Molecular Pathology 18 (1), 11-21

Suite de la liste des Publications et Recherches du Dr Ahmed Chenna :

Synthesis of the Fully Protected Phosphoramidite of the Benzene-DNA Adduct, N 2-(4-Hydroxyphenyl)-2′-Deoxyguanosine and Incorporation of the Later into DNA Oligomers.

A Chenna, RC Gupta, RR Bonala, F Johnson, B Hang

Nucleosides, Nucleotides and Nucleic Acids 27 (8), 979-991

Characterization of a novel proximity immunoassay for the quantitative determination of HER2 protein expression and HER2 homodimerization in formalin-fixed, paraffin-embedded …

J Winslow, Y Shi, Y Tan, X Jin, R Dua, E Penuel, A Mukherjee, J Sperinde, …

Breast Cancer Research and Treatment 106 (1 Suppl), S88

Detection of nucleic acid sequences by cleavage and separation of tag-containing structures.

A Chenna, V Xiao, S Singh

US Patent App. 11/447,753

The ERB family receptor dimerization in glioblastoma—An eTag assay analysis of 23 cases.

MR Hameed, L Sharer, E Cho, S Aisner, L Cao, Y Tan, A Mukherjee, …

Journal of Clinical Oncology 24 (18_suppl), 1582-1582

Methods and compositions for enhancing detection in determinations employing cleavable electrophoretic tag reagents.

A Chenna, S Singh

US Patent 7,037,654

Kits employing generalized target-binding e-tag probes.

S Singh, T Matray, A Chenna

US Patent 7,001,725

ErbB/HER pathway profiling in formalin-fixed paraffin embedded preclinical xenograft models using multiplexed proximity-based assays.

R Dua, Y Shi, L Cao, A Mukherjee, Y Tan, H Pannu, J Pannu, L Jarvis, …

International Conference on Molecular Targets and Cancer Therapeutics, AACR …

Kits employing oligonucleotide-binding e-tag probes.

S Singh, T Matray, A Chenna

US Patent 6,955,874

Sets of oligonucleotide-binding e-tag probes.

S Singh, T Matray, A Chenna

US Patent 6,916,612

Correlation of ErbB activation status and clinical response in Herceptin treated breast cancer patients.

A Mukherjee, J Pannu, L Cao, S Gangakhedkar, Y Tan, R Dua, H Tahir, …

Cancer Research 65 (9 Supplement), 869-870

Multiplexed assay for assessing ErbB/HER receptor pathways in formalin-fixed and paraffin-embedded cancer cell lines.

Y Shi, R Dua, A Mukherjee, L Cao, Y Tan, L Jarvis, H Pannu, TN Nguyen, …

Cancer Research 65 (9 Supplement), 1354-1354

Methods and compositions for enhancing detection in determinations employing cleavable electrophoretic tag reagents.

A Chenna, S Singh

US Patent App. 10/494,879

Multiplexed analysis by chromatographic separation of molecular tags.

A Chenna, T Matray, V Hernandez, H Hooper, S Singh

US Patent App. 10/918,876

Sets of generalized target-binding e-tag probes.

S Singh, T Matray, A Chenna

US Patent App. 10/779,255

Suite de la liste des Publications et Recherches du Dr Ahmed Chenna :

Sets of generalized target-binding e-tag probes.

S Singh, T Matray, A Chenna

US Patent 6,770,439

Erratum to”Miscoding properties of 1, N 6-ethanoadenine, a DNA adduct derived from reaction with the antitumor agent 1, 3-bis (2-chloroethyl)-1-nitrosourea”-[Mut. Res. 531 …

B Hang, A Chenna, AB Guliaev, B Singer

Mutation Research-Fundamental and Molecular Mechanisms of Mutagenesis 1 (546 …

Multiplex mRNA assay using electrophoretic tags for high-throughput gene expression analysis.

H Tian, L Cao, Y Tan, S Williams, L Chen, T Matray, A Chenna, S Moore, …

Nucleic acids research 32 (16), e126-e126

Methods for detecting a plurality of analytes by mass spectrometry.

TJ Matray, VS Hernandez, A Chenna, H Hooper, S Singh

US Patent 6,649,351

Monooxygenase assays.

S Singh, A Chenna, H Salimi-Moosavi, I Gibbons

US Patent App. 10/465,475

Miscoding properties of 1, N6-ethanoadenine, a DNA adduct derived from reaction with the antitumor agent 1, 3-bis (2-chloroethyl)-1-nitrosourea.

B Hang, A Chenna, AB Guliaev, B Singer

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 531 (1 …

Suite de la liste des Publications et Recherches du Dr Ahmed Chenna :

Monooxygenase assays.

S Singh, A Chenna, H Salimi-Moosari, I Gibbons

US Patent 6,632,630

Miscoding properties of 1, N-ethanoadenine, a DNA adduct derivedfrom reaction with the antitumor agent 1, 3-bis (2-chloroethyl)-1-nitrosourea.

B Hang, AB Guliaev, A Chenna, B Singer

Simultaneous multiplexed toxicogenomic and toxicoproteomic profiling.

S Singh, D Tabor, T Tian, L Chen, L Cao, S Williams, T Matray, A Chenna, …

TOXICOLOGICAL SCIENCES 72, 98-98

Synthesis of 8-(Hydroxymethyl)-3,N4-etheno-2‘-deoxycytidine, a Potential Carcinogenic Glycidaldehyde Adduct, and Its Site-Specific Incorporation into DNA …

A Chenna, A Perry, B Singer

Chemical research in toxicology 13 (3), 208-213

Synthesis of para-benzoquinone and 1, 3-bis (2-chloroethyl) nitrosourea adducts and their incorporation into oligonucleotides.

A Chenna, H Maruenda, B Singer

IARC scientific publications, 89-101

Differential cleavage of oligonucleotides containing the benzene-derived adduct, 1, N6-benzetheno-dA, by the major human AP endonuclease HAP1 and Escherichia coli exonuclease …

B Hang, A Chenna, J Sagi, B Singer

Carcinogenesis 19 (8), 1339-1343

Synthesis of 1,N6-Ethano-2‘-deoxyadenosine, a Metabolic Product of 1,3-Bis(2-chloroethyl)nitrosourea, and Its Incorporation into Oligomeric DNA.

H Maruenda, A Chenna, LK Liem, B Singer

The Journal of Organic Chemistry 63 (13), 4385-4389

A single cyclic p-benzoquinone adduct can destabilize a DNA oligonucleotide duplex.

J Sagi, A Chenna, B Hang, B Singer

Chemical research in toxicology 11 (4), 329-334

Sequence context is an important determinant in the mutagenic potential of 1, N6-ethenodeoxyadenosine (epsilonA): formation of epsilonA basepairs and elongation in defined …

V Litinski, A Chenna, J Sagi, B Singer

Carcinogenesis 18 (8), 1609-1615

Synthesis of a Benzene Metabolite Adduct, 3‘‘-Hydroxy-1,N2-benzetheno-2‘-deoxyguanosine, and Its Site-Specific Incorporation into DNA Oligonucleotides.

A Chenna, B Singer

Chemical research in toxicology 10 (2), 165-171

An unusual mechanism for the major human apurinic/apyrimidinic (AP) endonuclease involving 5′ cleavage of DNA containing a benzene-derived exocyclic adduct in the absence of …

B Hang, A Chenna, H Fraenkel-Conrat, B Singer

Proceedings of the National Academy of Sciences 93 (24), 13737-13741

Replication of O4-methylthymine-containing oligonucleotides: Effect of 3′ and 5′ flanking bases on formation and extension of O4-methylthymine· guanine basepairs.

S Rao, A Chenna, M Slupska, B Singer

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 356 (2 …

Enzymological repair of exocyclic DNA adducts formed by environmental carcinogens.

B Singer, B Hang, A Chenna

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 212, 70-TOXI

1, N6-Ethenoadenine and 3, N4-ethenocytosine are excised by separate human DNA glycosylases.

B Hang, A Chenna, S Rao, B Singer

Carcinogenesis 17 (1), 155-157

Large Scale Synthesis of p-Benzoquinone-2′-Deoxycytidine and p-Benzoquinone-2′-Deoxyadenosine Adducts and Their Site-Specific Incorporation into DNA Oligodeoxyribonucleotides.

A Chenna, B Singer

Chemical research in toxicology 8 (6), 865-874

The benzene metabolite p-benzoquinone forms adducts with DNA bases that are excised by a repair activity from human cells that differs from an ethenoadenine glycosylase.

A Chenna, B Hang, B Rydberg, E Kim, K Pongracz, WJ Bodell, B Singer

Proceedings of the National Academy of Sciences 92 (13), 5890-5894

All four known cyclic adducts formed in DNA by the vinyl chloride metabolite chloroacetaldehyde are released by a human DNA glycosylase.

MK Dosanjh, A Chenna, E Kim, H Fraenkel-Conrat, L Samson, B Singer

Proceedings of the National Academy of Sciences 91 (3), 1024-1028

Characterization of 2′-deoxycytidine and 2′-deoxyuridine adducts formed in reactions with acrolein and 2-bromoacrolein.

A Chenna, CR Iden

Chemical research in toxicology 6 (3), 261-268

Characterization of thymidine adducts formed by acrolein and 2-bromoacrolein.

A Chenna, RA Rieger, CR Iden

Carcinogenesis 13 (12), 2361-2365

Functionalized Benzocyclo-octenones: Synthesis and Chemistry.

GRPJR Ahmed Chenna, John Donnelly, Kevin J. McCullough

Journal of the Chemical Society, Perkin Transactions 1, 261-270

Aspects of the chemistry of some benzocyclo-octanes.

A Chenna

University of Strathclyde

1, 3-bis (2-chloroethyl) nitrosourea adducts and their incorporation into.

A Chenna, H Maruenda, B Singer

High HER2 Expression Correlates with Response to the Combination of Lapatinib and Trastuzumab.

PG Nuciforo, V Serra, L Prudkin, J Cortes

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موقع مدينة قمار، منارة العلم والتنوير ومعين المعرفة والعرفان ، زهرة المدائن الجزائرية وجوهرة الصحراء.

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